WAN NURUL NAZNEEM BINTI WAN OTHMAN

Experienced Natural Products Chemistry researcher with expertise in the extraction, isolation, purification, and characterization of bioactive compounds from natural sources. Proficient in chromatographic and analytical techniques, including HPLC, LC-MS, flash chromatography, and CPC. Experienced in research project management, method development, scientific publication, and industry collaboration, with a strong interest in translating research outcomes into commercial applications.

• Wan Nurul Nazneem Wan Othman, Liew Sook Yee, Khaw Kooi Yeong, Murugaiyah Vikneswaran, Marc Litaudon, Khalijah Awang. (2016). Cholinesterase inhibitory activity of isoquinoline alkaloids from three Cryptocarya species (Lauraceae). Bioorganic & Medicinal Chemistry, 24, 4464–4469. https://doi.org/10.1016/j.bmc.2016.07.043.
• Wan Nurul Nazneem Wan Othman, Yasodha Sivasothy, Liew Sook Yee, Jamaludin Mohamad, Mohd Azlan Nafiah, Kartini Ahmad, Marc Litaudon, Khalijah Awang. (2017). Alkaloids from Cryptocarya densiflora Blume (Lauraceae) and their cholinesterase inhibitory activity. Phytochemistry Letters, 21, 230–236. https://doi.org/10.1016/j.phytol.2017.07.002.
• Wan Nurul Nazneem Wan Othman, Fatimah Salim, Nor Nadirah Abdullah, Syahrul Imran Abu Bakar, Khalijah Awang, Lalith Jayasinghe, Nor Hadiani Ismail. (2022). (R)-13a-Densinoldizine, a new phenanthroindolizidine alkaloid from Cryptocarya densiflora Blume (Lauraceae) and molecular docking against SARS-CoV-2. Natural Product Communications, 17(8), 1–8. https://doi.org/10.1177/1934578X221114227.
• Norfaizah Osman, Azeana Zahari, Hazrina Hazni, Wan Nurul Nazneem Wan Othman, Nurulfazlina Edayah Rasol, Nor Hadiani Ismail, Pierre Champy, Mehdi A. Beniddir, Marc Litaudon, Khalijah Awang. (2023). Isolation and characterization of compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the aid of LCMS/MS molecular networking. Separations, 10(2), 74. https://doi.org/10.3390/separations10020074.
• Wan Nurul Nazneem Wan Othman, Fatimah Salim, Azeana Zahari, Khalijah Awang, Nor Hadiani Ismail. (2023). Alkaloids of Cryptocarya griffithiana Wight (syn. Cryptocarya infectoria Miq.) and their chemotaxonomic significance. Biochemical Systematics and Ecology, 109, 104667. https://doi.org/10.1016/j.bse.2023.104667.
• Adiez Sapura Azmi, Ahmed Mediani, Wan Abdul Muiz Wan Zainal Abidin, Wan Nurul Nazneem Wan Othman, Geoffrey A. Cordell, Fatimah Salim. (2024). Phytochemical variation between hydrochloric and tartaric acid-derived alkaloidal extracts of Erythrina fusca Lour. leaves: A proton NMR-based approach. South African Journal of Botany, 168, 430–451. https://doi.org/10.1016/j.sajb.2024.03.040.
• Mufeda Ahmed Hazea Gazaem, Wan Nurul Nazneem Wan Othman, Syed Adnan Ali Shah, Mustapha Salihu, Azeana Zahari, Siti Hajar Sadiran, Fatimah Salim. (2025). New hydroxylated metabolite derived from the microbial biotransformation of 11α-acetoxyprogesterone by the endophytic fungus Phyllosticta sp. 16L1 and its cytotoxic activity. Steroids, 216, 109584. https://doi.org/10.1016/j.steroids.2025.109584.
• Wan Nurul Nazneem Wan Othman, A. Hamid A. Hadi. (2014). Alkaloids isolated from the bark of Cryptocarya infectoria. Presented at the International Conference on Natural Products, Palm Garden Hotel, Putrajaya, Malaysia, 18–19 March 2014.
• Wan Nurul Nazneem Wan Othman, Mat Ropi Mukhtar, A. Hamid A. Hadi, Khalijah Awang. (2009). Alkaloids isolated from the leaves of Cryptocarya infectoria. Presented at the Malaysian Natural Product International Seminar (MNPIS) 2009 Silver Jubilee, M.S. Garden Hotel, Kuantan, Pahang, Malaysia, 23–24 November 2009.
• Wan Nurul Nazneem Wan Othman, Mat Ropi Mukhtar, A. Hamid A. Hadi, Khalijah Awang. (2009). Alkaloids isolated from the bark of Cryptocarya densiflora. Presented at the 5th Mathematics and Physical Sciences Graduate Congress 2009, Faculty of Science, Chulalongkorn University, Thailand, 7–9 December 2009.
• Wan Nurul Nazneem Wan Othman, Khalijah Awang. (2014). Alkaloids isolated from the leaves of Cryptocarya densiflora. Presented at the 3rd International Seminar on Chemistry 2014, Aula Pusat Studi Bahasa Jepang, Jatinangor Campus, Universitas Padjadjaran, Bandung, Indonesia, 20–21 November 2014.
• Wan Nurul Nazneem Wan Othman, Yasodha Sivasothy, Liew Sook Yee, Jamaludin Mohamad, Mohd Azlan Nafiah, Kartini Ahmad, Marc Litaudon, Khalijah Awang. (2017). Alkaloids from Cryptocarya densiflora Blume (Lauraceae) and their cholinesterase inhibitory activity. Presented at the International Malaysian – French Scientific Conference, Institute of Research Management & Monitoring (IPPP), University of Malaya, Kuala Lumpur, Malaysia, 18–19 December 2017.
• Registration Committee Member, International Conference on Molecular Chemistry 2008, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia, 25th – 27th November 2008.
• Registration, Souvenir & Sponsorship Committee Member, International Malaysian – French Scientific Conference, Institute of Research Management & Monitoring (IPPP), University of Malaya, Kuala Lumpur, Malaysia, 18th – 19th December 2017.
• Judge and co-moderator for oral presentations, Malaysian Natural Product International Seminar (MNPIS) 2022, Hilton Hotel, Kota Kinabalu, Sabah, Malaysia, 21st – 23rd September 2022.

• Age: 41 yrs.
• Date of Birth: 1st February 1985
• Nationality: Malaysian
• Gender: Female
• Marital Status: Married
• IC No.: 850201-03-5594