Ts Dr Shalini Krishnan
Lecturer
Kuala Ketil,02
Summary
Experienced researcher specializing in cancer cell line studies, nanoformulation development, and molecular biology techniques. Concurrently serving as a lecturer in biomedical science, with teaching responsibilities in biochemistry for MBBS students. Adept at bridging research and education to foster critical scientific thinking and practical application. Graduated with foundational knowledge in medicine and genetics and hands-on experience gained through academic projects and internships. Demonstrates strong teamwork, problem-solving, and time-management skills. Prepared to start a career and make meaningful contributions with commitment and drive.
Overview
2026
2026
years of professional experience
Work History
Lecturer
AIMST University
Bedong, Kedah
3 2020 - Current
- Working as a Lecturer in Biochemistry and Genetic Unit, Medical and Biomedical Department at AIMST University, Kedah, Malaysia.
Research Assistant
AIMST University
01.2019 - 04.2025
Proposed study involves developing nanobioconjugate based on Poly (D,L-lactide-co-glycolide) (PLGA) coated with chitosan. The nanobioconjugate carries anti-EGFR Monoclonal Antibody (mAb) to target TNBCs, anti-mouse Transferrin Receptor (TfR) antibody for drug delivery through the host endothelial system and siRNA (small interfering RNA) to specifically silence TNBCS overexpressed gene mTOR (Mammalian target of rapamycin) and to improve the anticancer potential of Paclitaxel (PTX). Methodology: siRNA-PTX loaded nanobioconjugated-mAb targeting TNBCs will be formulated and characterized. In vitro studies will be performed using TNBC and spheroid cells. EGFR, mTOR expression at mRNA and protein levels will be quantified using real time PCR and western blotting, respectively. Further assessment of cell cycle events on TNBC and spheroid cells after transfection will be investigated using flow cytometry. Subsequently, in vivo studies will be done using athymic mice model to confirm the targeting ability of the novel siRNA-PTX loaded nanobioconjugated-mAb. Outcome/Output: We aim to develop siRNA-PTXloaded nanobioconjugated-mAb specifically targeting TNBCs. Cancer statistics show that among all cancer cases in Malaysia, breast cancer is most prevalent. Hence our idea of developing siRNA loaded nanobioconjugated-mAb has tremendous therapeutic potential in Malaysia. This approach can also be used for targeted chemotherapy in breast cancer treatment.
Research Assistant
AIMST University
08.2016 - 12.2018
- Worked as research assistant under Dr.Vijayan in Triple Negative Breast Cancer Project and studied on molecular mechanisms PAC-PLGA-PEG loaded immunonanoscaffold targeting triple negative breast cancer.
Research Assistant
AIMST University
04.2015 - 07.2016
- Worked as research assistant under Dr.Anne (biochemistry/biotechnolgy department) in Acute Myeloid Leukaemia project in AIMST University, Kedah.
Document Coordinator
SM Biomed Sdn Bhd
02.2014 - 03.2015
- Worked as Document Coordinator at SM Biomed Sdn Bhd, Sungai Petani, Kedah, Malaysia.
Industrial Trainee
University Sains Malaysia
06.2013 - 09.2013
- Industrial trainee in University Sains Malaysia, Pulau Pinang (CDR).
Education
Ph.D. - Medical Genetics
University of Science Malaysia
USM,Kepala Batas 04.2001 -
Skills
- EXCEL
SPSS
Microsoft Word
Bioinformatics software (BLAST)
Molecular Modelling software (Chimera and Rasmol)
A leader with strong determination, passion and perseverance who encourages group to get things done and preserve the harmony within the group by making everyone feels included
Capable of completing any assignments, tasks or projects in timely fashion Able to manage people
Always curious about everything and find most of the subjects and topics interesting and fascinating
Love to learn new things with enthusiasm, whether in class or on my own
A careful and a disciplined person, always in control of my emotions and not vice versa
Always think things through, examine them from all sides and able to change my mind
Courageous person who speak up for what is right even there is opposition
A loyal and dedicated team mate, always do my share work hard for the success of my group (project work)
Educationalbackground - Highereducations
- PhD, Medical Genetics, Advanced Medical and Dental Institute, USM, Penang
- Appointed as Professional technologist by Malaysia Board of Technologists (MBOT)- 2025
- Appointed as Graduated technologist by Malaysia Board of Technologists (MBOT) -2024
- MSc, Medical Biochemistry, Aimst University/University of Science Malaysia
- BSc (Hons), Biotechnology, Aimst University
Webinarsworkshops
- Principles of Good Manufacturing Practice (GMP) and Hazard Analysis Critical Control Points (HACCP) in the Animal Feed Industry Webinars, 15/03/2024
- Becoming the Editor's Pick - Best Practices in Manuscript Writing, 19/01/2024
- Introduction to Good Laboratory Practice, 05/10/2023
- Biosafety talk 2023, 29/09/2023
- Fundamental Health Research by Elsevier
- Standardizing FFPE Nucleic Acid Extraction for Clinical Cancer Genomics
- Reproducible, Hands-free Protein Sample Preparation with Covaris AFA
Publications
- Pharmaceutical Nanotechnology, 2.69, : Communicate- Current developments in targeted molecular therapy of triple-negative breast cancer by mTOR siRNA nanoparticles., 02/7/2025
- Journal of Young Pharmacists, 2024- EGFR-mTOR siRNA loaded immunonanoparticles for targeted chemotherapy of triple negative breast cancer
- Eur.Chemical.Bull, 3.71, Development of mTOR siRNA anchored PTX nanoparticles for the treatment of triple-negative cancer (TNCB), 2023
- Rapports De Pharmacie, 4.41, A review on pandemic coronavirus (COVID-19): THE PAST., Venugopal Vijayan, Krishnan Shalini, Vasanth Raj Palanimuthu, T. Sankarankutty Subin, Jayaraja Kumar, Ng Siew Kit
- PLOSONE, 4.41, Anti-EGFR anchored paclitaxel loaded PLGA nanoparticles for the treatment of triple negative breast cancer. In-vitro and in-vivo anticancer activities, November 2018, Venugopal Vijayan, Krishnan Shalini, V.Yugesvaran, Teh HY, Siventhiran Balakrishnan, Vasanth Raj Palanimuthu
- Current Pharmaceutical Design, 3.0, Effect of Paclitaxel-Loaded PLGA Nanoparticles on MDA-MB Type Cell Lines; Apoptosis and Cytotoxicity Studies., October 2018, Venugopal Vijayan, Krishnan Shalini
- Rapports De Pharmacie, A short communication on PLGA as a magic polymer for the targeted drug delivery system., Vol.3 (2), 2017, 356-358, Shalini krishnan, Vijayan Venugopal
Extracurricular Activities
- Blood Donation Drive Date: 10th and 11th June 2025 Venue: AIMST University
- Sparkling Smiles Date:25th MAY 2025 Venue: SJKT Palanisamy
- Joyful Feast: Autism Awareness Edition Date:13th April 2025 Venue: NASOM, Alor Setar
- Stitching 101: Suturing Skills Workshop Date: 22nd March 2025 Venue: CSC, Aimst University
- Sparkling Smiles Date: 16th March 2025 Venue: Persatuan Kanak Kanak Khas, Sungai Petani
- Joyful Feast: Buka Puas Edition Date: 15th March 2025 Venue: Persatuan Rumah Anak Yatim Daerah Kuala Muda
- Organized medical camp MEDICUBE Date: December to February 2024
- Joyful Feast: Christmas Edition Date: 22 December 2024 Location: Pusat Jagaan Glory
- Organized Sparkling Smiles camp for primary school students Date: 1 Septermber 2024 Location: SJK(T) Bedong & Date: 18 December 2024 Location: SJK(T) Ladang Sungai Puntar
- Organized Joyful Feast with orphanage students : Deepavali Edition Date: 1 December 2024 Location: Arutjyothi Vallala Mandram Sg.Petani, Kedah
- Organized Blood Donation Drive Date: 5-6 November 2024 Location: Mutaiyas Foyer
- Organized Blood Donation Drive Date: 7-8 May 2024 Location: Clinical Skills Centre Date: 5-6 November 2024 Location: Mutaiyas Foyer
- Organized a Suturing Skill Workshop Date: 9 March 2024 Location: Clinical Skills Centre &: 12 October 2024 Location: Clinical Skills Centre
- Organized a medical camp MEDICUBE Date: December to April 2024 (5 medical camps
- Organized Blood Donation Drive Date: October 2023 Location: Mutaiyas Foyer
- Organized a Happiness Project (Mental Health Talk) on 28 October 2023 Location: Zoom Meeting
- Organized a sign language workshop for the students and staff of AIMST University on Hand That Speak on 14 and 15 October 2023 Location: LR01 Library
- Organized seminars and workshops for SPM students before the examination - EDIFY-SPM Seminar Edition on 09 September 2023 at Kanagawa Lecture Theatre,AIMST University
- Organized and participated in a beach cleaning program named -Together We Can on12 September 2023 atTanjung Dawai Beach
- Organized a medical camp (Medicube)- Date:6 May 2023- Location: Dewan UMNO, Bukit Selambau,
- Organized and participate in Blood Donation Drive (124 successful donars) on 18-20 April 2023 at Mutaiyas Foyer AIMST University
- Organized a Euphoria - A Charity Concert - Date: 15 October 2022 Location: Great Hall AIMST Univeristy
- Organized and participated in Community Medical Camp held on 13 August 2022 Location: Kampung Kuala Sin, Bukit Selambau, Kedah
- Organized Mental Health talk collabration with Rotart club Bandar Sungai Petani on online: Date: 10 January 2022 Location: Instagram Live
- 2022 - Present, AIMST Rotary Club Advisor 2021 - Present, Member of Center of Excellent Nanotechnology at AIMST University 2018-2019,
- Member of EWFR: Teacher for primary school at SJKT Batu Pekaka, Kuala Ketil Kedah. Teaching English subject for primary school student form B40.
- February 2008 - December 2008, Chairman of Club Cyber in Sekolah Menengah Kuala Ketil
- February 2008 - December 2008, Vice Chairman of Scout’s Club in Sekolah Menangah Kuala Ketil
- May 2006 - January 2008, School Athlete (District representative)
Training
- Appointed as trainers for Global Immersion Programme - Internship with participants from Saveetha University. (10 April - 9th May 2025). Delivered a talk on 'CRISPR and the Future of Genetic Medicine: From Cures to Controversy'
- 5th International Conference on Molecular Biology and Biotechnology 2022 (5th ICMBB2022)., Oral presentation
- 4th International Conference on Molecular Biology and Biotechnology 2021., Oral presentation
- ASEAN-QA Online Forum 2020: Drivers for Change: Quality Assurance in Times of Disruption and Innovation.
- IECBBB2020 E-Conference International E-Conference on Biotechnology, Bioinformatics, and Biomedicine 2020, Poster Presentation
- International conference of pharmaceutical sciences and medicines 2018, 3rd August 2018, Burapha University, Thailand., Poster Presentation
- International conference of life-style diseases organized by AIMST university, October 2017, Poster Presentation
References
- SR. PROF. DR. K.R.SETHURAMA, Dean of Faculty of Medicine, Aimst University
- Dr.Anne Jeyachisty, Senior Lecturer, Universiti Kuala Lumpur Royal College of Medicine Perak
- Prof. Dr.Vijayan Venugopal, Senior Lecturer, Balajee Vidyapeeth University, Pondicherry, India
- Assoc Prof Datin Dr. Shahrul Bariyah, Supervisor for PhD, Institut Perubatan dan Pergigian Termaju, Universiti Sains Malaysia
Timeline
Research Assistant
AIMST University
01.2019 - 04.2025
Research Assistant
AIMST University
08.2016 - 12.2018
Research Assistant
AIMST University
04.2015 - 07.2016
Document Coordinator
SM Biomed Sdn Bhd
02.2014 - 03.2015
Industrial Trainee
University Sains Malaysia
06.2013 - 09.2013
Ph.D. - Medical Genetics
University of Science Malaysia
04.2001 -
Lecturer
AIMST University
3 2020 - Current
Similar Profiles
Umashankar KrishnappaUmashankar Krishnappa
In-charge Director & Associate Professor at AIMST UniversityIn-charge Director & Associate Professor at AIMST University
SHALINI SILVAKUMADSHALINI SILVAKUMAD
Intern/Student at Aimst UniversityIntern/Student at Aimst University
DINESHKUMAR LAKSHMI NARAYANANDINESHKUMAR LAKSHMI NARAYANAN
Lecturer at AIMST UniversityLecturer at AIMST University
DARREN NUMDARREN NUM
Car Mechanic at Jay Ganesh AutosCar Mechanic at Jay Ganesh Autos
YUSUF HAJI OTHMANYUSUF HAJI OTHMAN
Associate Professor at Sultan Abdul Halim Mu'adzam Shah International Islamic UniversityAssociate Professor at Sultan Abdul Halim Mu'adzam Shah International Islamic University